Which term refers to substances required in large amounts by the human body for energy?

The term that refers to substances required in large amounts by the human body for energy is macro-nutrients. Macro-nutrients are the nutrients that provide the energy necessary for bodily functions and include carbohydrates, proteins, and fats. Each of these has specific roles in the body; for instance, carbohydrates are the body's main source of energy, proteins support tissue repair and growth, and fats provide a dense source of energy as well as essential fatty acids that the body needs for various functions.

In contrast, micro-nutrients, such as vitamins and minerals, are required in smaller amounts and play critical roles in bodily processes, but they do not provide energy directly. Vitamins help with various biochemical functions, and minerals support structural and regulatory functions in the body. Therefore, macro-nutrients are distinct as they are the primary sources of energy, making them essential for supporting overall health and activity levels.